Patrick W K Lee Selected Research

Reoviridae Infections

1/2012	Exploring host factors that impact reovirus replication, dissemination, and reovirus-induced cell death in cancer versus normal cells in culture.
6/2010	Oncogenic Ras promotes reovirus spread by suppressing IFN-beta production through negative regulation of RIG-I signaling.
1/2010	Z-FA-FMK as a novel potent inhibitor of reovirus pathogenesis and oncolysis in vivo.
3/2004	Optimization of reovirus production from mouse L-929 cells in suspension culture.
3/2002	Oncolytic reovirus against ovarian and colon cancer.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Patrick W K Lee Research Topics

Disease

29	Neoplasms (Cancer) 01/2019 - 03/2002
5	Breast Neoplasms (Breast Cancer) 07/2016 - 03/2002
5	Reoviridae Infections 01/2012 - 03/2002
3	Neoplasm Metastasis (Metastasis) 11/2014 - 06/2003
2	Triple Negative Breast Neoplasms 07/2016 - 01/2015
2	Ovarian Neoplasms (Ovarian Cancer) 02/2013 - 03/2002
1	Starvation 02/2017
1	Circulating Neoplastic Cells 11/2014
1	Peritoneal Neoplasms 02/2013
1	Infections 07/2012
1	Kaposi Sarcoma (Kaposi's Sarcoma) 02/2012
1	Prostatic Neoplasms (Prostate Cancer) 04/2011
1	Adenocarcinoma 04/2011
1	Myocarditis (Carditis) 01/2010
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2010
1	Persistent Infection 01/2010
1	Bacterial Infections (Bacterial Infection) 06/2008
1	Colonic Neoplasms (Colon Cancer) 02/2008
1	Hypersensitivity (Allergy) 02/2008
1	Carcinogenesis 06/2005
1	Urinary Bladder Neoplasms (Bladder Cancer) 11/2004
1	Lymphoma (Lymphomas) 09/2003
1	Transitional Cell Carcinoma 05/2003
1	Virus Diseases (Viral Diseases) 12/2002
1	Ataxia Telangiectasia (Louis Bar Syndrome) 07/2002

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 07/2016 - 05/2003
3	AntigensIBA 01/2014 - 11/2010
3	Antiviral Agents (Antivirals)IBA 07/2012 - 06/2005
2	NAD (NADH)IBA 01/2019 - 01/2014
2	Peptides (Polypeptides)IBA 02/2017 - 11/2010
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 07/2016 - 01/2015
2	Aldehyde DehydrogenaseIBA 01/2015 - 01/2011
2	Neoplasm Antigens (Tumor Antigens)IBA 01/2014 - 11/2010
2	CytokinesIBA 02/2013 - 04/2011
2	Protein Isoforms (Isoforms)IBA 05/2011 - 01/2011
2	Phosphotransferases (Kinase)IBA 02/2008 - 07/2002
2	AntibodiesIBA 06/2005 - 01/2003
2	Viral ProteinsIBA 12/2002 - 03/2002
1	Beclin-1IBA 02/2017
1	Sirolimus (Rapamycin)FDA Link 02/2017
1	Sirtuin 1IBA 12/2016
1	AntioxidantsIBA 12/2016
1	ChromatinIBA 07/2016
1	Hormones (Hormone)IBA 07/2016
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 07/2016
1	ClaudinsIBA 07/2016
1	Immunologic Factors (Immunomodulators)IBA 05/2015
1	Interferon Type IIBA 01/2015
1	Biomarkers (Surrogate Marker)IBA 11/2014
1	Therapeutic UsesIBA 02/2013
1	InterferonsIBA 01/2012
1	Histocompatibility Antigens Class IIBA 04/2011
1	Small Interfering RNA (siRNA)IBA 01/2011
1	Messenger RNA (mRNA)IBA 06/2010
1	KetonesIBA 01/2010
1	DipeptidesIBA 01/2010
1	phenylalanylalanineIBA 01/2010
1	MDL 201053IBA 01/2010
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 06/2009
1	Biotin (Vitamin H)FDA Link 06/2009
1	ChromiumIBA 02/2008
1	Saline SolutionIBA 11/2004
1	SuspensionsIBA 03/2004
1	raf KinasesIBA 05/2003
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 05/2003
1	Epidermal Growth Factor (EGF)IBA 05/2003
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2003
1	Methionine (L-Methionine)FDA Link 03/2002

Therapy/Procedure

19	Therapeutics 01/2019 - 03/2002
4	Immunotherapy 02/2013 - 11/2004
1	Drug Therapy (Chemotherapy) 01/2019
1	Immunomodulation 02/2013
1	Oncolytic Virotherapy 09/2003
1	Radiotherapy 06/2003
1	Injections 06/2003